As a member of myosin light chain kinase (MYLK) family with serine/threonine specificity, MYLK4 belongs to an enzyme encoded by MYLK4 gene. MYLK4 gene may play a vital role in muscle development. MYLK4 (Myosin Light Chain Kinase Family Member 4, also known as SgK085) is located on human chromosome 6p25.2. The MYLK4 protein is ubiquitously expressed in kidney, thyroid and other tissues. Structurally, the encoded protein is reported to be 44508 Da in mass. The MYLK4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, etc. MYLK4 is related to Focal Adhesion and Apelin signaling pathway. MYLK4 is also related to transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MYLK3. MYLK4 is associated with some diseases, including Deafness, Autosomal Recessive 14 and Cardiomyopathy, Familial Restrictive, 2.