TMEM169 (Transmembrane Protein 169) is located on human chromosome 2q35. The TMEM169 protein is biasedly expressed in brain, thyroid and other tissues. Structurally, the encoded TMEM169 protein is reported to be 33611 Da in mass. The TMEM169 (also known as FLJ34263) gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 235 organisms have orthologs with human gene TMEM169.