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卵母细胞特异性KHDC1抗体
产品名称 Anti-KHDC1 Anti-KH domain containing 1 Antibody 产品介绍
靶标: KHDC1 产品别名: C6orf147; C6orf148; Em:AC019205.8; NDG1; bA257K9.4; KHDC1; KH domain containing 1; KH domain containing 1; KH homology domain-containing protein 1; KH homology domain containing 1; Putative KHDC1-like protein; 卵母细胞特异性KHDC1; 背景信息: KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4). |
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