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Bcdin3d抗体
交货期:1周


产品名称
Anti-Bcdin3d
Anti-BCDIN3 domain containing Antibody
产品介绍
靶标:

Bcdin3d


产品别名:

4930556P03Rik; AV138748; Bcdin3d; BCDIN3 domain containing; BCDIN3 domain containing; RNA 5'-monophosphate methyltransferase; BCDIN3 domain-containing protein; pre-miRNA 5'-monophosphate methyltransferase; probable methyltransferase BCDIN3D;


背景信息:
O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His, acting as a capping enzyme by protecting tRNA(His from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
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