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1号染色体开放阅读框86抗体
产品名称 Anti-Faap20 Anti-Fanconi anemia core complex associated protein 20 Antibody 产品介绍
靶标： Faap20 产品别名： 2610002J02Rik； Faap20； Fanconi anemia core complex associated protein 20； Fanconi anemia core complex associated protein 20； Fanconi anemia core complex-associated protein 20； FANCA-associated protein of 20 kDa； Fanconi anemia-associated protein of 20 kDa； likely orthologue of H. sapiens chromosome 1 open reading frame 86 (C1orf86)； 1号染色体开放阅读框86； 背景信息： C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1. |
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