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丝氨酸棕榈酰转移酶长链碱性亚基3(SPTLC3)抗体
交货期:1周


产品名称
Anti-SPTLC3
Anti-serine palmitoyltransferase long chain base subunit 3 Antibody
产品介绍
靶标:

SPTLC3


产品别名:

C20orf38; LCB 3; LCB2B; LCB3; SPT 3; SPT3; SPTLC2L; dJ718P11; dJ718P11.1; hLCB2b; SPTLC3; serine palmitoyltransferase long chain base subunit 3; serine palmitoyltransferase long chain base subunit 3; serine palmitoyltransferase 3; long chain base biosynthesis protein 2b; long chain base biosynthesis protein 3; serine palmitoyltransferase, long chain base subunit 2-like (aminotransferase 2); serine-palmitoyl-CoA transferase 3; 丝氨酸棕榈酰转移酶长链碱性亚基3(SPTLC3);


背景信息:
The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT; EC 2.3.1.50), which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al., 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3), depending on the tissue in which biosynthesis occurs (Hornemann et al., 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit, SSSPTA (MIM 613540) and SSSPTB (MIM 610412), that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010],
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