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RAGEF2蛋白抗体
产品名称 Anti-RAPGEF6 Anti-Rap guanine nucleotide exchange factor 6 Antibody 产品介绍
靶标： RAPGEF6 产品别名： KIA001LB； PDZ-GEF2； PDZGEF2； RA-GEF-2； RAGEF2； RAPGEF6； Rap guanine nucleotide exchange factor 6； Rap guanine nucleotide exchange factor 6； rap guanine nucleotide exchange factor 6； PDZ domain containing guanine nucleotide exchange factor (GEF) 2； PDZ domain-containing guanine nucleotide exchange factor 2； PDZ domain-containing guanine nucleotide exchange factor I； Rap guanine nucleotide exchange factor (GEF) 6； RAGEF2蛋白； 背景信息： function:Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Ras-GEF domain.,subcellular location:Upon binding to M-Ras, it translocates to the plasma membrane.,subunit:Interacts with the second PDZ domain of human PTP1e.,tissue specificity:Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas., |
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