The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Kinesins also play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. Belonging to the Kinesin-like protein family, KIF19 is a 998 amino acid protein that contains one kinesin-motor domain, a domain that creates force in order to bind and move on microtubules. The gene encoding KIF19 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. There are three isoforms of KIF19 that are produced as a result of alternative splicing events.