ZFAND2A is a 171 amino acid protein containing two AN1-type zinc fingers. AN1-type zinc fingers contain six conserved cysteines, two histidines and have a dimetal (zinc)-bound alpha/beta fold. The gene encoding ZFAND2A maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.