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重组3号染色体开放阅读框39蛋白
产品名称 Recombinant POMGNT2 Recombinant protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) protein 产品介绍
基因名： POMGNT2 产品别名： AGO61； C3orf39； GTDC2； MDDGA8； MDDGC8； POMGNT2； protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)； protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)； protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2； glycosyltransferase-like domain containing 2； glycosyltransferase-like domain-containing protein 2； protein O-mannose beta-1,4-N-acetylglucosaminyltransferase 2； 3号染色体开放阅读框39； 背景信息： C3orf39, also known as AGO61, is a 580 amino acid secreted protein belonging to the glycosyltransferase 61 family. C3orf39 is encoded by a gene that maps to human chromosome 3p25.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3. |
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