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重组锌指蛋白93
交货期:1周

产品名称
Recombinant ZNF93
Recombinant zinc finger protein 93 protein
产品介绍
基因名:

ZNF93


产品别名:

HPF34; HTF34; TF34; ZNF505; ZNF93; zinc finger protein 93; zinc finger protein 93; zinc finger protein 93; zinc finger protein 505; zinc finger protein HTF34; 锌指蛋白93;


背景信息:
Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). Not able to repress expression of all subtypes of L1 elements. Binds to the 5 end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs. 50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression (PubMed:25274305).
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