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重组SNRNP200蛋白
产品名称 Recombinant SNRNP200 Recombinant small nuclear ribonucleoprotein U5 subunit 200 protein 产品介绍
基因名： SNRNP200 产品别名： ASCC3L1； BRR2； HELIC2； RP33； U5-200KD； SNRNP200； small nuclear ribonucleoprotein U5 subunit 200； small nuclear ribonucleoprotein U5 subunit 200； U5 small nuclear ribonucleoprotein 200 kDa helicase； BRR2 homolog； U5 snRNP-specific 200 kDa protein； activating signal cointegrator 1 complex subunit 3-like 1； bad response to refrigeration 2 homolog； small nuclear ribonucleoprotein 200kDa (U5)； small nuclear ribonucleoprotein, U5 200kDa subunit； SNRNP200蛋白； 背景信息： Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010] |
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