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重组周期素D结合蛋白1
产品名称 Recombinant Ccndbp1 Recombinant cyclin D-type binding-protein 1 protein 产品介绍
基因名: Ccndbp1 产品别名: AU022347; DIP1; GCIP; Maid; SECC-8; SSEC-8; Ccndbp1; cyclin D-type binding-protein 1; cyclin D-type binding-protein 1; cyclin-D1-binding protein 1; grap2 and cyclin-D-interacting protein; maternal Id-like protein; maternal inhibition of differentiation; stage specific embryonic cDNA-8 protein; 周期素D结合蛋白1; 背景信息: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas. |
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