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重组Rap鸟嘌呤核苷酸交换因子2蛋白
交货期:1周

产品名称
Recombinant RAPGEF2
Recombinant Rap guanine nucleotide exchange factor 2 protein
产品介绍
基因名:

RAPGEF2


产品别名:

CNrasGEF; NRAPGEP; PDZ-GEF1; PDZGEF1; RA-GEF; RA-GEF-1; RAGEF; Rap-GEP; nRap GEP; RAPGEF2; Rap guanine nucleotide exchange factor 2; Rap guanine nucleotide exchange factor 2; rap guanine nucleotide exchange factor 2; PDZ domain containing guanine nucleotide exchange factor (GEF) 1; PDZ domain-containing guanine nucleotide exchange factor 1; RA(Ras/Rap1A-associating)-GEF; Rap guanine nucleotide exchange factor (GEF) 2; cyclic nucleotide ras GEF; neural RAP guanine nucleotide exchange protein; ras/Rap1-associating GEF-1; Rap鸟嘌呤核苷酸交换因子2;


背景信息:
SummaryMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
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