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重组FCP1蛋白
交货期:1周

产品名称
Recombinant CTDP1
Recombinant CTD phosphatase subunit 1 protein
产品介绍
基因名:

CTDP1


产品别名:

CCFDN; FCP1; CTDP1; CTD phosphatase subunit 1; CTD phosphatase subunit 1; RNA polymerase II subunit A C-terminal domain phosphatase; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1; CTD of POLR2A, phosphatase of, subunit 1; TFIIF-associating CTD phosphatase 1; serine phosphatase FCP1a; transcription factor IIF-associating CTD phosphatase 1; FCP1蛋白;


背景信息:
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
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